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PhaseXplorer SDL (Nadia Erkamp)

PhaseXplorer is an autonomous platform that studies phase-separating systems. It explores under which conditions a mixture splits into two or more distinct phases, helping to understand cell organisation and disease, and to engineer new materials such as food and drug-delivery systems. Used by researchers across biology, chemistry, and materials science.

Built around Confocal.nl’s NL5+ point-scanning confocal, driven by Micro-Manager, the open-source Fiji/ImageJ-based microscope control software — the microscope is a programmable participant in the experiment loop, not just a viewer at the end.

Capabilities

  • Autonomous mapping of multivariate phase space
  • Confocal imaging of droplets and condensates
  • Drastic reduction in material consumption (10,000× less than manual)
  • Throughput improvement (~100× faster than manual screens)

Located at

Ceres (ICMS / TU/e). Visitors welcome on request.

What is coming

Move from understanding when phase separation happens to optimising materials for specific properties. Collaboration with fellow ICMS members will be key.

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Questions or training? Ask the super-user

Nadia ErkampAssistant Professor · PhaseXplorer lead

For general facility access or new project scoping, contact superresolution@tue.nl.

Reference

Reference: Erkamp et al., ACS Nano (2025).